Submucous fibroids are a type of uterine fibroid that develops in the uterine cavity, just beneath the endometrium. Diagnosis is based on a combination of clinical signs and additional tests. Click here to join and get more information
Clinical (suggestive signs)
Metrorrhagia (heavy, prolonged, irregular bleeding)
Menorrhagia (very heavy periods)
Secondary anemia due to blood loss
Pelvic pain or cramps Infertility or repeated miscarriages
Diagnostic Tests Pelvic Ultrasound (especially transvaginal)
First-line examination
Shows a rounded, well-circumscribed intrauterine mass pushing back into the endometrial cavity.
Hysterosonography (ultrasound with saline injection)
Provides better visualization of the uterine cavity and confirms the submucosal nature.
Diagnostic Hysteroscopy Provides direct visualization of the uterine cavity.
Considered the gold standard: it allows both diagnosis and sometimes treatment (fibroid resection).
Pelvic MRI Performed in certain cases (before surgery, infertility assessment, or if other tests are inconclusive).
Specifies the exact location, number, and size of fibroids.
Preventing Submucous
Fibroids Preventing uterine fibroids (including submucous fibroids) is not always possible, as the exact cause is multifactorial (hormonal, genetic, environmental). However, certain protective factors and preventive measures can reduce the risk or limit progression:
Lifestyle and Diet Maintain a healthy weight: Obesity increases circulating estrogen, which promotes fibroids.
Balanced diet: favor fruits, vegetables, legumes, and fiber, and limit red meat, processed foods, and excess saturated fats.
Regular consumption of vitamin D (rich foods or moderate sun exposure): a deficiency is associated with a higher risk of fibroids.
Limit excessive alcohol and caffeine, which can influence hormonal metabolism
Healthy Lifestyle
Regular physical activity: reduces inflammation, improves hormonal balance, and helps control weight.
Stress reduction: Chronic stress can disrupt hormonal balance (cortisol, estrogen).
Hormonal and gynecological factors
Pregnancy and breastfeeding: These protect against the development of fibroids.
Hormonal contraceptives: Certain pills can help regulate cycles and reduce symptoms, but they do not always prevent the development of fibroids.
Regular monitoring: An annual gynecological visit, with an ultrasound if necessary, can detect fibroids early and prevent complications
Medical Approaches
These primarily aim to control symptoms (bleeding, pain, anemia) and reduce the size or remove the fibroid.
Progestins: regulate cycles and reduce bleeding.
GnRH analogs (e.g., leuprorelin, goserelin): induce temporary artificial menopause → reduce fibroid volume, used in preparation for surgery.
Selective progesterone receptor modulators (e.g., ulipristal acetate, depending on availability and local recommendations).
Hormonal intrauterine device (levonorgestrel IUD): reduces heavy periods.
Anemia treatment: iron, vitamins, transfusion if necessary.
Surgical Treatments
Operative hysteroscopy: Standard treatment for submucosal fibroids → direct endoscopic resection.
Myomectomy: Removal of the fibroid while preserving the uterus (if multiple or large fibroids).
Hysterectomy: Removal of the uterus, as a last resort, especially if fibroids recur and there is no desire for pregnancy.
Minimally invasive methods (subject to availability)
Uterine artery embolization: Reduction of blood flow to the fibroid, causing it to shrink.
Focused ultrasound (HIFU): Targeted destruction of the fibroid using ultrasound.
Possible natural (complementary) approaches
Plants rich in antioxidants and anti-inflammatories (turmeric, green tea, red berries): can limit associated inflammation.
Some studies suggest a protective role for omega-3 fatty acids (oily fish, flaxseeds, walnuts).